小鼠大脑中芳香化酶免疫反应性神经元中雌激素受体的存在。
Presence of estrogen receptors in aromatase-immunoreactive neurons in the mouse brain.
作者信息
Tsuruo Y, Ishimura K, Osawa Y
机构信息
Department of Anatomy, School of Medicine, University of Tokushima, Japan.
出版信息
Neurosci Lett. 1995 Jul 28;195(1):49-52. doi: 10.1016/0304-3940(95)11779-v.
The present study was undertaken to demonstrate estrogen receptors in aromatase-immunoreactive neurons showed the immunoreactivity for estrogen receptors in the cell nuclei in the medial subdivision of the bed nucleus of the stria terminalis and the posterodorsal division of the medial amygdaloid nucleus, but a few did in the medial preoptic area. These results suggest that aromatase-immunoreactive neurons in the former two areas are regulated by steroids through estrogen receptors in their cell nuclei.
本研究旨在证明，芳香化酶免疫反应性神经元中的雌激素受体在终纹床核内侧亚区和杏仁内侧核后背部的细胞核中显示出雌激素受体免疫反应性，但在视前内侧区仅有少数显示。这些结果表明，前两个区域中芳香化酶免疫反应性神经元受类固醇通过其细胞核中的雌激素受体调控。
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