Pérez S E, Adrio F, Rodríguez M A, Anadón R, Rodríguez-Moldes I
Department of Fundamental Biology, Faculty of Biology, University of Santiago de Compostela, Spain.
Neurosci Lett. 1995 Aug 4;195(2):85-8. doi: 10.1016/0304-3940(95)11786-v.
The extrahypohysial projections of the neurosecretory preoptic nucleus (PON) of the electric ray were studied with the aid of an antibody against nitric oxide synthase (NOS). PON neurons were the only NOS-like-immunoreactive (NOS-ir) cells in the brain. These neurons gave rise to both hypophysial and extrahypophysial NOS-ir projections. Some fibres coursed from the PON to the neurointermediate lobe in the preoptic-hypophysial tract. Other NOS-ir fibres coursed either rostrally or caudally forming terminal fields in the telencephalon (subpallial region), diencephalon (preoptic nucleus, ventrolateral thalamus and posterior recess nucleus), tuberal region (area tegmentalis ventralis and substantia nigra), mesencephalon (lateral tegmentum), rhombencephalon (isthmal nucleus, vagal viscerosensory column and ventrolateral reticular area) and the spinal cord (intermediate horn). The possible involvement of the extrahypophysial PON projections in neuroregulation of visceral centres is discussed.
借助抗一氧化氮合酶（NOS）抗体，对电鳐神经分泌视前核（PON）的垂体外投射进行了研究。PON神经元是脑中唯一呈现一氧化氮合酶样免疫反应性（NOS-ir）的细胞。这些神经元产生垂体和垂体外的NOS-ir投射。一些纤维从PON沿视前 - 垂体束延伸至神经中间叶。其他NOS-ir纤维向前或向后延伸，在端脑（皮质下区域）、间脑（视前核、腹外侧丘脑和后隐窝核）、结节区（腹侧被盖区和黑质）、中脑（外侧被盖）、后脑（峡核、迷走内脏感觉柱和腹外侧网状区）以及脊髓（中间角）形成终末区。文中讨论了垂体外PON投射在内脏中枢神经调节中的可能作用。
