Barzó P, Tuka P, Molnár L, Kiss J I
Szent Ferenc Kórház III, Tüdöbelgyógyászat.
Orv Hetil. 1995 Oct 8;136(41):2231-6.
Authors offer a survey about an aspect forming a clinical entity called bronchiolitis obliterans organizing pneumonia, by two of their patients' presentation. In Case 1 the process manifested in form of a disseminated, small spotted, diffuse shadow, causing serious resting hypoxia. Diagnosis was supported by histological examination of a substance obtained by small surgical thoracotomy. Five months' therapy of Imuran and altogether 15 months' therapy of Prednisolon resulted in recovery. Second patient's symptoms and the shadow representated in the left upper lung field on chest X-ray, proposed the probability of a tumour. The lesion removed surgically, together with the left upper lobe, proved to be the clinical appearance that constitutes histologically the subject of this paper. Surgery alone resulted in definitive recovery. Disease can be proved on the basis of histological picture and it's important to sunder it primarily from bronchiolitis obliterans as well as from other interstitial pulmonary diseases.
作者通过两名患者的病例，对一种构成临床实体的疾病——闭塞性细支气管炎并机化性肺炎的一个方面进行了综述。病例1中，病变表现为弥漫性、小斑点状、弥漫性阴影，导致严重的静息性低氧血症。通过小开胸手术获取的组织进行组织学检查支持了诊断。使用硫唑嘌呤治疗5个月，泼尼松龙总共治疗15个月后康复。第二名患者的症状及胸部X光片上左上肺野的阴影提示肿瘤的可能性。手术切除的病变组织，连同左上叶，经组织学检查证实为本文所述的临床表现。仅手术就实现了彻底康复。该病可根据组织学表现得以证实，重要的是首先将其与闭塞性细支气管炎以及其他间质性肺病区分开来。
