Avital A, Uwyyed K, Picard E, Godfrey S, Springer C
Institute of Pulmonology, Hadassah University Hospital, Jerusalem, Israel.
Pediatr Pulmonol. 1995 Jul;20(1):40-3. doi: 10.1002/ppul.1950200108.
The purpose of this study was to compare the pathogens obtained by oropharyngeal suction (OPS) and bronchoalveolar lavage (BAL) in children with chronic pulmonary infections. Forty-four children (mean age of 6.1 years; range 4 months to 15 years) were included in the study (27 children with recurrent localized lung infection, 5 with bronchiectasis, 5 with cystic fibrosis, 2 with foreign body aspiration, 2 with bronchiolitis obliterans, and 3 with recurrent episodes of cough and shortness of breath). In 27 out of 44 BAL samples (61%) bacterial cultures were positive. The sensitivity of OPS in detecting the same BAL pathogen was 89% (24/27 samples), the specificity was 94% (16/17 samples), and the predictive value was 91% (40/44 samples). Hemophilus influenzae beta-lactamase negative was the main organism recovered from BAL in non-cystic fibrosis patients with recurrent or persistent pneumonia. We conclude that OPS is a simple and efficient noninvasive procedure which may be helpful in the diagnosis and treatment of recurrent or chronic pulmonary infection.
本研究的目的是比较慢性肺部感染患儿经口咽吸引（OPS）和支气管肺泡灌洗（BAL）获取的病原体。44名儿童（平均年龄6.1岁；范围4个月至15岁）纳入本研究（27名反复局限性肺部感染儿童、5名支气管扩张症儿童、5名囊性纤维化儿童、2名异物吸入儿童、2名闭塞性细支气管炎儿童和3名反复咳嗽和气短发作儿童）。44份BAL样本中有27份（61%）细菌培养呈阳性。OPS检测相同BAL病原体的敏感性为89%（24/27份样本），特异性为94%（16/17份样本），预测值为91%（40/44份样本）。β-内酰胺酶阴性流感嗜血杆菌是反复或持续性肺炎非囊性纤维化患者BAL中分离出的主要病原体。我们得出结论，OPS是一种简单有效的非侵入性操作，可能有助于反复或慢性肺部感染的诊断和治疗。
