1994年威康基金会讲座。成人疾病的胎儿起源。
The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease.
作者信息
Barker D J
机构信息
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, U.K.
出版信息
Proc Biol Sci. 1995 Oct 23;262(1363):37-43. doi: 10.1098/rspb.1995.0173.
PMID:7479990
Abstract
Recent findings suggest that many human fetuses have to adapt to a limited supply of nutrients and in doing so they permanently change their physiology and metabolism. These 'programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related disorders: stroke, diabetes and hypertension.
摘要
最近的研究结果表明，许多人类胎儿不得不适应有限的营养供应，在此过程中，他们的生理和新陈代谢会发生永久性变化。这些“程序化”的变化可能是日后许多疾病的根源，包括冠心病以及相关病症：中风、糖尿病和高血压。
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