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1994年威康基金会讲座。成人疾病的胎儿起源。

The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease.

作者信息

Barker D J

机构信息

MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, U.K.

出版信息

Proc Biol Sci. 1995 Oct 23;262(1363):37-43. doi: 10.1098/rspb.1995.0173.

DOI:10.1098/rspb.1995.0173
PMID:7479990
Abstract

Recent findings suggest that many human fetuses have to adapt to a limited supply of nutrients and in doing so they permanently change their physiology and metabolism. These 'programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related disorders: stroke, diabetes and hypertension.

摘要

最近的研究结果表明,许多人类胎儿不得不适应有限的营养供应,在此过程中,他们的生理和新陈代谢会发生永久性变化。这些“程序化”的变化可能是日后许多疾病的根源,包括冠心病以及相关病症:中风、糖尿病和高血压。

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The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease.1994年威康基金会讲座。成人疾病的胎儿起源。
Proc Biol Sci. 1995 Oct 23;262(1363):37-43. doi: 10.1098/rspb.1995.0173.
2
Fetal nutrition and cardiovascular disease in later life.胎儿营养与成年后的心血管疾病
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Maternal nutrition, fetal nutrition, and disease in later life.孕期营养、胎儿营养与成年后的疾病
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In utero programming of chronic disease.慢性疾病的子宫内编程
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A new model for the origins of chronic disease.一种慢性病起源的新模型。
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Fetal, infant, and childhood growth are predictors of coronary heart disease, diabetes, and hypertension in adult men and women.胎儿期、婴儿期及儿童期的生长发育情况是成年男性和女性患冠心病、糖尿病及高血压的预测指标。
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Maternal nutrition in relation to fetal and placental growth.与胎儿及胎盘生长相关的母体营养
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Intrauterine programming of coronary heart disease and stroke.冠心病和中风的宫内编程
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