Shemesh J, Apter S, Rozenman J, Lusky A, Rath S, Itzchak Y, Motro M
Cardiac Rehabilitation Institute, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel-Hashomer, Israel.
Radiology. 1995 Dec;197(3):779-83. doi: 10.1148/radiology.197.3.7480756.
To evaluate the accuracy of double-helix computed tomography (CT) in coronary artery calcification detection and quantification.
One hundred sixty patients with coronary disease (135 men, 25 women; age range, 45-62 years), of whom 138 had obstructive (stenosis of > 50% of diameter; n = 129) or mild (< 50% stenosis; n = 9) coronary artery disease (CAD) and 22 had normal coronary arteries (per angiographic findings), and 56 age-matched healthy control subjects underwent double-helix CT.
Double-helix CT findings indicated that calcification was significantly more prevalent in patients with CAD (> 83%) than in patients with normal coronary arteries (27%) or in healthy control subjects (34%; P < .01). Sensitivity in detecting obstructive CAD was high (91%); however, specificity was low (52%) because of calcification in nonobstructive lesions. Comparison of double-helix CT and angiographic findings indicated that double-helix CT was 84% accurate with positive and negative predictive values of 89% and 59%, respectively.
Double-helix CT is a useful noninvasive method for detection and quantification of coronary artery calcification.
评估双螺旋计算机断层扫描（CT）在冠状动脉钙化检测和定量分析中的准确性。
160例冠心病患者（135例男性，25例女性；年龄范围45 - 62岁），其中138例患有阻塞性（直径狭窄>50%；n = 129）或轻度（<50%狭窄；n = 9）冠状动脉疾病（CAD），22例冠状动脉正常（根据血管造影结果），以及56例年龄匹配的健康对照者接受了双螺旋CT检查。
双螺旋CT检查结果表明，CAD患者中钙化的发生率（>83%）显著高于冠状动脉正常患者（27%）或健康对照者（34%；P <.01）。检测阻塞性CAD的敏感性较高（91%）；然而，由于非阻塞性病变中的钙化，特异性较低（52%）。双螺旋CT与血管造影结果的比较表明，双螺旋CT的准确性为84%，阳性预测值和阴性预测值分别为89%和59%。
双螺旋CT是一种用于检测和定量分析冠状动脉钙化的有用的非侵入性方法。
