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一名系统性红斑狼疮患者合并胸腺瘤和纯红细胞再生障碍性贫血。

Thymoma and pure red cell aplasia in a patient with systemic lupus erythematosus.

作者信息

Duchmann R, Schwarting A, Poralla T, Meyer zum Büschenfelde K H, Hermann E

机构信息

I. Medical Department, University of Mainz, Germany.

出版信息

Scand J Rheumatol. 1995;24(4):251-4. doi: 10.3109/03009749509100884.

DOI:10.3109/03009749509100884
PMID:7481592
Abstract

We present the case of a female patient with a diagnosis of systemic lupus erythematosus (SLE) at the age of 54 years. At the age of 63 years, she suffered from malignant thymoma and 3 years after removal of the thymoma a diagnosis of pure red cell aplasia (PRCA) was established. This is, to our knowledge, the first report of the occurrence of SLE, thymoma and PRCA in the same patient. The case is discussed with regard to the already known associations between these diseases.

摘要

我们报告一例54岁女性患者,其诊断为系统性红斑狼疮(SLE)。63岁时,她患了恶性胸腺瘤,在胸腺瘤切除3年后确诊为纯红细胞再生障碍性贫血(PRCA)。据我们所知,这是同一患者发生SLE、胸腺瘤和PRCA的首例报告。本文结合这些疾病之间已知的关联对该病例进行了讨论。

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Thymoma and pure red cell aplasia in a patient with systemic lupus erythematosus.一名系统性红斑狼疮患者合并胸腺瘤和纯红细胞再生障碍性贫血。
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Ann Hematol. 2025 Apr;104(4):2189-2206. doi: 10.1007/s00277-025-06315-z. Epub 2025 Mar 19.
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A tale of autoimmunity: thymoma, thymectomy, and systemic lupus erythematosus.自身免疫疾病的故事:胸腺瘤、胸腺切除术和系统性红斑狼疮。
Clin Rheumatol. 2020 Jul;39(7):2227-2234. doi: 10.1007/s10067-020-05061-z. Epub 2020 Apr 10.
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Rational management approach to pure red cell aplasia.
纯红细胞再生障碍性贫血的合理治疗方法。
Haematologica. 2018 Feb;103(2):221-230. doi: 10.3324/haematol.2017.175810. Epub 2017 Dec 7.
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Systemic lupus erythematosus complicated with thymoma and pure red cell aplasia (PCRA). CR of both complications following thymectomy and allogeneic haematopoietic SCT (HSCT), but persistence of antinuclear antibodies (ANA).系统性红斑狼疮合并胸腺瘤和纯红细胞再生障碍性贫血(PRCA)。胸腺切除和异基因造血干细胞移植(HSCT)后两种并发症均完全缓解,但抗核抗体(ANA)持续存在。
Bone Marrow Transplant. 2014 Jul;49(7):982-3. doi: 10.1038/bmt.2014.68. Epub 2014 May 12.