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在软下疳流行期间,急诊科对波动型腹股沟淋巴结炎进行切开引流与穿刺抽吸的比较

Incision and drainage versus aspiration of fluctuant buboes in the emergency department during an epidemic of chancroid.

作者信息

Ernst A A, Marvez-Valls E, Martin D H

机构信息

Louisiana State University, Department of Medicine, New Orleans, USA.

出版信息

Sex Transm Dis. 1995 Jul-Aug;22(4):217-20. doi: 10.1097/00007435-199507000-00003.

Abstract

GOAL OF THIS STUDY

To compare outcomes of incision and drainage with packing to needle aspiration of purulent buboes in patients with presumed chancroid. The safety and efficacy of incision and drainage were compared with that of needle aspiration.

STUDY DESIGN AND METHODS

The study was a prospective randomized, nonblinded clinical trial carried out from April 1992, to January 1994 in an inner city emergency department. A consecutive sample of 27 adults with fluctuant inguinal buboes presumed or proven to be chancroid or lymphogranuloma venereum were eligible for inclusion. Patients were excluded if they were believed to have buboes secondary to disease other than chancroid. After informed consent was obtained, patients had buboes drained by needle aspiration or by incision and drainage with packing according to a random numbers table.

RESULTS

Twenty-seven patients were included in the study (22 men and 5 women), with 12 randomized to incision and drainage and 15 to aspiration. The mean age was 35.7 +/- 13 years. Genital ulcer or bubo pus cultures for Haemophilus ducreyi were positive in seven patients, negative in 15 patients, and not done in five patients. Follow-up was obtained for 23 (85%) patients, 11 of whom had incision and drainage and 12 of whom had aspirations. No adverse effects were reported in either group.

CONCLUSION

Incision and drainage is an effective method for treating fluctuant buboes and may be preferable to traditional needle aspiration considering the frequency of required re-aspirations in the study patients. Limitations of this study include lack of complete laboratory testing and lack of follow-up of all patients.

摘要

本研究目的

比较在疑似软下疳患者中,切开引流加填塞术与针吸术治疗脓性腹股沟淋巴结炎的效果。将切开引流的安全性和有效性与针吸术进行比较。

研究设计与方法

本研究为前瞻性随机、非盲临床试验,于1992年4月至1994年1月在市中心的急诊科开展。连续纳入27例腹股沟淋巴结波动感明显、疑似或确诊为软下疳或性病性淋巴肉芽肿的成年患者。若患者被认为腹股沟淋巴结炎继发于软下疳以外的其他疾病,则将其排除。获得知情同意后,根据随机数字表,患者通过针吸术或切开引流加填塞术排出腹股沟淋巴结脓液。

结果

27例患者纳入研究(22例男性和5例女性),12例随机分配至切开引流组,15例分配至针吸组。平均年龄为35.7±13岁。7例患者的生殖器溃疡或腹股沟淋巴结脓液培养结果显示杜克雷嗜血杆菌阳性,15例阴性,5例未进行培养。23例(85%)患者获得随访,其中11例接受切开引流,12例接受针吸术。两组均未报告不良反应。

结论

切开引流是治疗波动感明显的腹股沟淋巴结炎的有效方法,考虑到本研究中患者需要重复针吸的频率,切开引流可能优于传统针吸术。本研究的局限性包括缺乏完整的实验室检测以及未对所有患者进行随访。

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