[淋巴肉芽肿病中人类血红蛋白红细胞内蛋白水解的变化]
[Changes in the intraerythrocytic proteolysis of human hemoglobin in lymphogranulomatosis].
作者信息
Pivnik A V, Rasstrigin N A, Kremenetskaia A M, Filippova M M, Karelin A A
出版信息
Ter Arkh. 1995;67(7):33-4.
PMID:7482302
Abstract
The data obtained on red cell hemolysates from 16 patients with Hodgkin's disease varying in age, sex, the disease stage and histology, time since the diagnosis served the basis for comparative evaluation of endogenic intraerythrocytic hemoglobin proteolysis and relevant products. The results show that Hodgkin's disease brings about a 10-15-fold increase in the quantity of accumulated hemoglobin alpha-chain fragments.
摘要
从16例霍奇金病患者的红细胞溶血产物中获取的数据，这些患者在年龄、性别、疾病分期、组织学类型以及诊断后的时间等方面存在差异，这些数据为内源性红细胞内血红蛋白蛋白水解作用及相关产物的比较评估提供了基础。结果表明，霍奇金病会使积累的血红蛋白α链片段数量增加10至15倍。
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