细螅间质细胞分化的调控。IV. 头部再生中神经细胞的定向分化取决于位置。
Regulation of interstitial cell differentiation in Hydra attenuata. IV. Nerve cell commitment in head regeneration is position-dependent.
作者信息
Yaross M S, Bode H R
出版信息
J Cell Sci. 1978 Dec;34:27-38. doi: 10.1242/jcs.34.1.27.
In hydra, nerve cells are a differentiation product of the interstitial cell, a multipotent stem cell. Nerve cell commitment was examined during head regeneration in Hydra attenuata. Within 3 h of head removal there is a 10- to 20-fold increase in nerve cell commitment in the tissue which subsequently forms the new head. Nerve cell commitment is unaltered in the remainder of the gastric region. This local increase in nerve cell commitment is responsible for about one half the new nerve cells formed during head regeneration, while one half differentiate from interstitial cells that migrate into the regenerating tip.
在水螅中，神经细胞是间充质细胞（一种多能干细胞）的分化产物。研究人员在细螅头部再生过程中检测了神经细胞的定向分化。在切除头部后的3小时内，随后形成新头部的组织中神经细胞的定向分化增加了10到20倍。胃区其余部分的神经细胞定向分化没有变化。神经细胞定向分化的这种局部增加约占头部再生过程中形成的新神经细胞的一半，而另一半则由迁移到再生顶端的间充质细胞分化而来。
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