Frolova I A
Lik Sprava. 1995 Jan-Feb(1-2):73-5.
A total of 83 patients with psoriasis were examined; of these, 53 individuals had disseminated forms of psoriasis (group 1), 30--generalized or global psoriatic erythroderma (group II). Studied in the peripheral blood were activity of interleukins--1 and 2 (IL-1 and 2), concentration of plasmic fibronektin and relative count of lymphocytes expressing receptors to urokinase. There have been revealed in group I patients moderate increase in IL-1 activity, apparent lowering of IL-2, reduction in concentration of plasmic fibronektin, decrease in relative count of lymphocytes expressing receptors to urokinase in both clinical groups. Negative correlation was established between the latter two parameters, which was the greatest in patients with psoriatic erythrodermia.
共检查了83例银屑病患者；其中，53例为播散型银屑病（第1组），30例为泛发性或全身性银屑病红皮病（第II组）。研究了外周血中白细胞介素-1和2（IL-1和IL-2）的活性、血浆纤维连接蛋白浓度以及表达尿激酶受体的淋巴细胞相对计数。在第1组患者中发现，IL-1活性中度升高，IL-2明显降低，血浆纤维连接蛋白浓度降低，两个临床组中表达尿激酶受体的淋巴细胞相对计数均减少。后两个参数之间存在负相关，在银屑病红皮病患者中最为显著。
