Geurs F, Baele G, Afschrift M
Department of Geriatrics, University Hospital, Ghent, Belgium.
Acta Clin Belg. 1995;50(4):238-41. doi: 10.1080/17843286.1995.11718453.
The occurrence of an acquired inhibitor of F VIII coagulant activity is a rare cause of a sometimes important bleeding diathesis. Antibodies against F VIII:C can spontaneously occur, mostly in elderly patients. Four elderly patients with such a typical clinical and biological syndrome are reported. No identifiable underlying disease was found and they responded favourably to an immunosuppressive treatment. In one patient plasmapheresis was successful.
