Nelson K H, Briner W, Cummins J
North Colorado Medical Center, Greeley, USA.
Am Fam Physician. 1995 Nov 1;52(6):1811-6.
Local corticosteroid injection therapy may be considered for many conditions commonly treated by the primary care physician. Chronic overuse and flawed biomechanics may lead to inflammation in areas easily accessible to injected local corticosteroids, including bursae, tendon sheaths and joints. It is generally preferable to mix the steroid preparation with an anesthetic agent to minimize the injection pain, provide immediate symptom relief and confirm the diagnosis. Local complications of corticosteroid injection include tendon and ligament weakening, bacterial infections of joints and related structures, and subcutaneous tissue atrophy. Systemic complications are rare but reportedly include hyperglycemia and adrenal axis suppression.
对于许多基层医疗医生通常治疗的病症，可考虑采用局部皮质类固醇注射疗法。长期过度使用和有缺陷的生物力学可能导致在易于注射局部皮质类固醇的部位发生炎症，包括滑囊、腱鞘和关节。通常最好将类固醇制剂与麻醉剂混合，以尽量减少注射疼痛、立即缓解症状并确诊。皮质类固醇注射的局部并发症包括肌腱和韧带变弱、关节及相关结构的细菌感染以及皮下组织萎缩。全身并发症很少见，但据报道包括高血糖和肾上腺轴抑制。
