Gargot D, Chaussade S, d'Alteroche L, Desbazeille F, Grandjouan S, Louvel A, Douvin J, Causse X, Festin D, Chapuis Y
Service d'Hépato-Gastroentérologie, Hôpital de Blois, France.
Am J Gastroenterol. 1995 Nov;90(11):2035-8.
We report two patients with large bowel submucosal diaphragm disease associated with nonsteroidal anti-inflammatory drugs (slow release form of diclofenac and phenylbutazone) who were admitted in 1990 and 1991 because of iron deficiency. At colonoscopy, the lumen of the ascending colon was divided into compartments by multiple thin circumferential mucosal membranes. Barium enema showed two short strictures in one patient. Right hemicolectomy was carried out on one patient. The other patient was simply advised to discontinue taking diclofenac and remains well. Such lesions are rare (10 cases have been reported) and resemble those previously described in the small bowel.
我们报告了两名患有与非甾体抗炎药（双氯芬酸缓释剂型和保泰松）相关的大肠黏膜下隔膜疾病的患者，他们分别于1990年和1991年因缺铁性贫血入院。结肠镜检查时，升结肠管腔被多个薄的环形黏膜膜分隔成多个腔室。钡剂灌肠显示其中一名患者有两个短缩窄。对一名患者实施了右半结肠切除术。另一名患者仅被建议停用双氯芬酸，目前情况良好。此类病变罕见（已报告10例），与先前在小肠中描述的病变相似。
