Chan C C, Whitcup S M, Solomon D, Nussenblatt R B
Laboratory of Immunology, National Eye Institute, Bethesda, MD 20892-1858, USA.
Am J Ophthalmol. 1995 Nov;120(5):671-3. doi: 10.1016/s0002-9394(14)72217-2.
To find an accurate and simple method to diagnose primary intraocular lymphoma.
We prospectively analyzed concentrations of interleukin-10, interleukin-1, interleukin-2, interleukin-4, and interleukin-6 in vitrectomy specimens from three patients with primary intraocular lymphoma and five patients with uveitis by enzyme-linked immunosorbent assay.
Interleukin-10 in the vitreous was detected in patients with primary intraocular lymphoma. Interleukin-10 levels correlated with clinical activity and the number of malignant cells.
Concentrations of interleukin-10 in the vitreous may be a helpful clue to both clinicians and pathologists in diagnosing primary intraocular lymphoma.
寻找一种准确、简便的方法来诊断原发性眼内淋巴瘤。
我们采用酶联免疫吸附测定法，对3例原发性眼内淋巴瘤患者和5例葡萄膜炎患者玻璃体切除标本中的白细胞介素-10、白细胞介素-1、白细胞介素-2、白细胞介素-4和白细胞介素-6浓度进行了前瞻性分析。
原发性眼内淋巴瘤患者的玻璃体中检测到白细胞介素-10。白细胞介素-10水平与临床活动度和恶性细胞数量相关。
玻璃体中白细胞介素-10的浓度可能对临床医生和病理学家诊断原发性眼内淋巴瘤有所帮助。
