Pinals R S
J Rheumatol. 1978 Fall;5(3):272-4.
A persistently normal erythrocyte sedimentation rate in the presence of active synovitis was found in 17 out of 500 patients with rheumatoid arthritis. These were compared with 17 age- and sex-matched random rheumatoid arthritis controls. The patients were mostly female (15/17) and seronegative (12/17). Other acute phase reactants were measured in some cases and were also normal. Athough erosion and deformity occurred in more than half, significant involvement was restricted to the small, peripheral joints. The limited mass of inflamed synovial tissue may account for the absence of an acute phase response.
在500例类风湿关节炎患者中，有17例在存在活动性滑膜炎时红细胞沉降率持续正常。将这些患者与17例年龄和性别匹配的随机选取的类风湿关节炎对照患者进行比较。这些患者大多为女性（15/17）且血清阴性（12/17）。在某些病例中还检测了其他急性期反应物，结果也均正常。虽然超过半数患者出现了侵蚀和畸形，但显著受累的仅限于小的外周关节。炎症滑膜组织量有限可能是缺乏急性期反应的原因。
