Jajić Z, Vuksic D, Jajić I
Klinika za fizikalnu medicinu, rehabilitaciju i reumatologiju, KB, Sestre milosrdnice, Zagreb.
Reumatizam. 1994;41(2):5-7.
The effect of chloroquine on acute phase reactants and clinical features in rheumatoid arthritis patients was evaluated. The patients had also one of nonsteroid antiinflammatory drugs therapy. Following acute phase reactans were evaluated: erythrocyte sedimentation rate and haptoglobin. The number of swollen and painful joints were also evaluated. All parameters were evaluated before the beginning of the therapy and each 3 months of medication during 9 months. The patients were analyzed by therapy effect and they were divided in 3 groups: all patients, only the patients who responded and the patients who did not respond on antimalarials. Assessed clinical and laboratory parameters were most improved in patients who responded on therapy. Acute phase reactants are markers of activity of illness, better CRP and less other haptoglobin and other parameters erythrocyte sedimentation rate and haemoglobin.
评估了氯喹对类风湿性关节炎患者急性期反应物和临床特征的影响。这些患者同时接受一种非甾体抗炎药治疗。评估了以下急性期反应物：红细胞沉降率和触珠蛋白。还评估了肿胀和疼痛关节的数量。在治疗开始前以及用药9个月期间每3个月对所有参数进行评估。根据治疗效果对患者进行分析，并将他们分为3组：所有患者、对抗疟药有反应的患者和无反应的患者。有反应的患者的评估临床和实验室参数改善最为明显。急性期反应物是疾病活动的标志物，较好的指标是C反应蛋白，较低的是其他如触珠蛋白以及其他参数如红细胞沉降率和血红蛋白。
