注射吸毒者中HIV-1血清阳转的危险因素：一项病例对照研究。
Risk factors for HIV-1 seroconversion among injection drug users: a case-control study.
作者信息
Chitwood D D, Griffin D K, Comerford M, Page J B, Trapido E J, Lai S, McCoy C B
机构信息
Comprehensive Drug Research Center, University of Miami School of Medicine, FL 33136, USA.
出版信息
Am J Public Health. 1995 Nov;85(11):1538-42. doi: 10.2105/ajph.85.11.1538.
Abstract
OBJECTIVES
A nested case-control study was conducted in Miami, Fla, to determine risk factors associated with human immunodeficiency virus type 1 (HIV-1) seroconversion among injection drug users.
METHODS
The study identified 21 incident cases of HIV-1 infection and 76 unmatched controls from two longitudinal cohorts of injection drug users. One cohort consisted of individuals who originally had been recruited from treatment centers; a second cohort was recruited from the "street." Logistic regression analyses that adjusted for age, gender, and race were performed.
RESULTS
The final model determined that the primary independent risk factor that best explained the risk for seroconversion was sharing injection equipment in the year prior to conversion; a marginal risk factor was presence of sexually transmitted disease during this same period.
CONCLUSIONS
Both an injection component and a sexual component play a role in seroconversion among injection drug users, although the injection component is much stronger.
摘要
目的
在佛罗里达州迈阿密开展了一项巢式病例对照研究，以确定注射吸毒者中与1型人类免疫缺陷病毒（HIV-1）血清转化相关的危险因素。
方法
该研究从两个注射吸毒者纵向队列中确定了21例HIV-1感染新发病例和76名不匹配的对照。一个队列由最初从治疗中心招募的个体组成；第二个队列是从“街头”招募的。进行了调整年龄、性别和种族的逻辑回归分析。
结果
最终模型确定，最能解释血清转化风险的主要独立危险因素是在转化前一年共用注射器具；同期存在性传播疾病是一个边缘危险因素。
结论
尽管注射因素的作用更强，但注射因素和性因素在注射吸毒者的血清转化中都起作用。
相似文献
1
Risk factors for HIV-1 seroconversion among injection drug users: a case-control study.注射吸毒者中HIV-1血清阳转的危险因素：一项病例对照研究。
Am J Public Health. 1995 Nov;85(11):1538-42. doi: 10.2105/ajph.85.11.1538.
2
Differences in risk factors for human immunodeficiency virus type 1 seroconversion among male and female intravenous drug users.男性和女性静脉注射吸毒者中1型人类免疫缺陷病毒血清转化风险因素的差异。
Am J Epidemiol. 1993 Apr 15;137(8):892-8. doi: 10.1093/oxfordjournals.aje.a116750.
3
Parenteral and sexual transmission of human immunodeficiency virus in intravenous drug users: a study of seroconversion. The Northern Italian Seronegative Drug Addicts (NISDA) Study.静脉注射吸毒者中人类免疫缺陷病毒的肠道外传播和性传播：血清转化研究。意大利北部血清阴性吸毒者（NISDA）研究。
Am J Epidemiol. 1992 Feb 1;135(3):225-33. doi: 10.1093/oxfordjournals.aje.a116275.
4
The harm reduction approach and risk factors for human immunodeficiency virus (HIV) seroconversion in injecting drug users, Amsterdam.
Am J Epidemiol. 1992 Jul 15;136(2):236-43. doi: 10.1093/oxfordjournals.aje.a116489.
5
A case-control study of HIV infection among incarcerated female drug users: impact of sharing needles and having drug-using sexual partners.在押女性吸毒者中 HIV 感染的病例对照研究：共用针具和有吸毒性伴侣的影响。
J Formos Med Assoc. 2011 Jul;110(7):446-53. doi: 10.1016/S0929-6646(11)60066-1.
6
HIV seroconversion and disinfection of injection equipment among intravenous drug users, Baltimore, Maryland.
Epidemiology. 1991 Nov;2(6):444-6. doi: 10.1097/00001648-199111000-00010.
7
AIDS risk reduction and reduced HIV seroconversion among injection drug users in Bangkok.曼谷注射吸毒者中艾滋病风险降低及艾滋病毒血清转化率下降
Am J Public Health. 1994 Mar;84(3):452-5. doi: 10.2105/ajph.84.3.452.
8
HIV, hepatitis B and sexual practices in the street-recruited injecting drug users of Calcutta: risk perception versus observed risks.加尔各答街头招募的注射吸毒者中的艾滋病毒、乙型肝炎与性行为：风险认知与实际观察到的风险
Int J STD AIDS. 1998 Apr;9(4):214-8. doi: 10.1258/0956462981922061.
9
Behavioral characteristics of seroconverted intravenous drug users.
Int J Addict. 1992 Dec;27(12):1413-21. doi: 10.3109/10826089209047359.
10
Weight loss associated with HIV seroconversion among injection-drug users.
J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 15;12(5):514-8. doi: 10.1097/00042560-199608150-00012.
引用本文的文献
1
Disparities of COVID-19 and HIV Occurrence Based on Neighborhood Infection Incidence in Philadelphia, Pennsylvania.基于宾夕法尼亚州费城邻里感染发病率的 COVID-19 和 HIV 发病差异。
Am J Public Health. 2022 Mar;112(3):408-416. doi: 10.2105/AJPH.2021.306538.
2
A review of network simulation models of hepatitis C virus and HIV among people who inject drugs.对注射吸毒人群中丙型肝炎病毒和 HIV 的网络模拟模型的回顾。
Int J Drug Policy. 2021 Feb;88:102580. doi: 10.1016/j.drugpo.2019.10.006. Epub 2019 Nov 15.
3
Barriers to practicing risk reduction strategies among people who inject drugs.注射吸毒者实施降低风险策略的障碍。
Addict Res Theory. 2016;24(1):62-68. doi: 10.3109/16066359.2015.1068301. Epub 2015 Jul 21.
4
A Mismatch between High-Risk Behaviors and Screening of Infectious Diseases among People Who Inject Drugs in Dar es Salaam, Tanzania.坦桑尼亚达累斯萨拉姆注射吸毒者中高风险行为与传染病筛查之间的不匹配
PLoS One. 2016 Feb 5;11(2):e0148598. doi: 10.1371/journal.pone.0148598. eCollection 2016.
5
Cross sectional study of factors associated to self-reported blood-borne infections among drug users.吸毒者自我报告的血源性病原体感染相关因素的横断面研究。
BMC Public Health. 2015 Nov 13;15:1122. doi: 10.1186/s12889-015-2442-6.
6
Opiate substitution treatment and HIV transmission in people who inject drugs: systematic review and meta-analysis.阿片类物质替代治疗与注射吸毒人群中 HIV 的传播：系统评价和荟萃分析。
BMJ. 2012 Oct 3;345:e5945. doi: 10.1136/bmj.e5945.
7
Development of a risk reduction intervention to reduce bacterial and viral infections for injection drug users.开发一种减少注射吸毒者细菌和病毒感染风险的干预措施。
Subst Use Misuse. 2013 Jan;48(1-2):54-64. doi: 10.3109/10826084.2012.722159. Epub 2012 Sep 27.
8
Skin and needle hygiene intervention for injection drug users: results from a randomized, controlled Stage I pilot trial.皮肤和针具卫生干预措施对注射吸毒者的效果：一项随机对照Ⅰ期试点试验的结果。
J Subst Abuse Treat. 2012 Oct;43(3):313-21. doi: 10.1016/j.jsat.2012.01.003. Epub 2012 Feb 14.
9
Suburban Poverty: Barriers to Services and Injury Prevention among Marginalized Women who Use Methamphetamine.郊区贫困：使用甲基苯丙胺的边缘女性在获取服务和预防伤害方面的障碍。
West J Emerg Med. 2011 Jul;12(3):284-92.
10
HIV risk behavior in treatment-seeking opioid-dependent youth: results from a NIDA clinical trials network multisite study.寻求治疗的阿片类药物依赖青少年中的 HIV 风险行为：NIDA 临床试验网络多中心研究的结果。
J Acquir Immune Defic Syndr. 2010 Sep;55(1):65-72. doi: 10.1097/QAI.0b013e3181d916db.
本文引用的文献
1
Geographical variations in the prevalence of HIV infection among drug users receiving ambulatory treatment in Spain.西班牙接受门诊治疗的吸毒者中艾滋病毒感染率的地域差异。
Int J Epidemiol. 1993 Apr;22(2):306-14. doi: 10.1093/ije/22.2.306.
2
Differences in risk factors for human immunodeficiency virus type 1 seroconversion among male and female intravenous drug users.男性和女性静脉注射吸毒者中1型人类免疫缺陷病毒血清转化风险因素的差异。
Am J Epidemiol. 1993 Apr 15;137(8):892-8. doi: 10.1093/oxfordjournals.aje.a116750.
3
Determinants of HIV-1 infection in intravenous drug users in Valencia, Spain, 1987-1991.
Int J Epidemiol. 1993 Jun;22(3):537-42. doi: 10.1093/ije/22.3.537.
4
Drug-related HIV risk behaviors and cocaine preference among injection drug users in Los Angeles.洛杉矶注射吸毒者中与毒品相关的艾滋病毒风险行为及对可卡因的偏好。
J Drug Educ. 1993;23(3):259-72. doi: 10.2190/GP3B-4KUD-T0UP-Y9FK.
5
Cross-validation in survival analysis.生存分析中的交叉验证。
Stat Med. 1993 Dec 30;12(24):2305-14. doi: 10.1002/sim.4780122407.
6
HIV seroconversion studies among intravenous drug users.
AIDS. 1994 Feb;8(2):263-5. doi: 10.1097/00002030-199402000-00016.
7
HIV seroconversion in intravenous drug users in San Francisco, 1985-1990.1985 - 1990年旧金山静脉注射吸毒者中的HIV血清转化情况。
AIDS. 1994 Feb;8(2):223-31. doi: 10.1097/00002030-199402000-00010.
8
Seroconversion in patients attending sexually transmitted disease clinics.性病门诊患者的血清转化
AIDS. 1994 Mar;8(3):351-5. doi: 10.1097/00002030-199403000-00009.
9
Attitudes toward narcotic addiction.
J Nerv Ment Dis. 1987 Nov;175(11):653-60. doi: 10.1097/00005053-198711000-00002.
10
Human immunodeficiency virus infection in heterosexual intravenous drug users in San Francisco.旧金山异性恋静脉吸毒者中的人类免疫缺陷病毒感染情况。
Am J Public Health. 1987 Feb;77(2):169-72. doi: 10.2105/ajph.77.2.169.
Zotero 插件