Hsu C K, Leo P, Shastry D, Meggs W, Weisman R, Hoffman R S
Mount Sinai School of Medicine, Emergency Medicine Residency Program, Beth Israel Hospital Medical Center, New York, NY, USA.
Arch Intern Med. 1995 Nov 13;155(20):2245-8.
An outbreak of cholinergic poisoning occurred in New York City during a 3-day period. Seven individuals from three families of South American origin were affected. Signs and symptoms of illness included dry skin, hyperthermia, tachycardia, dilated pupils, agitation, and hallucinations. Onset of illness in all cases was temporally associated with consumption of a tea that was labeled "Paraguay Tea" and was purchased from a grocery store specializing in South American foods. Paraguay tea, made from the leaves of the holly, Ilex paraguariensis, contains caffeine and theophylline and is a popular beverage in South America. Samples of the tea analyzed with gas chromatography contained belladonna alkaloids but neither caffeine nor theophylline. An investigation by the New York City Department of Health personnel determined that the tea was from a single lot, imported by one distributor, and sold at one grocery store. Unsold inventories of the tea were quarantined, and no further cases of anticholinergic poisoning were reported.
在纽约市的三天时间里发生了一起胆碱能中毒事件。来自三个南美裔家庭的七个人受到了影响。疾病的体征和症状包括皮肤干燥、体温过高、心动过速、瞳孔散大、烦躁不安和幻觉。所有病例的发病时间都与饮用一种标有“巴拉圭茶”的茶有关，这种茶是从一家专门经营南美食品的杂货店购买的。巴拉圭茶由冬青叶（巴拉圭冬青）制成，含有咖啡因和茶碱，是南美一种受欢迎的饮料。用气相色谱法分析的茶样中含有颠茄生物碱，但不含咖啡因和茶碱。纽约市卫生部门人员的调查确定，这种茶来自同一批次，由一家经销商进口，并在一家杂货店销售。未售出的茶叶库存被隔离，此后未再报告抗胆碱能中毒病例。
