[用于肽固相合成和液相柱色谱的自动化“SynChrom”系统。II. 在肽固相合成和液相柱色谱中的应用]
[The automated "SynChrom" system for solid-phase synthesis of peptides and liquid column chromatography. II. Use in the solid-phase synthesis of peptides and liquid column chromatography].
作者信息
Baru M B, Cherskiĭ V V, Danilov A V, Moshnikov S A, Mustaeva L G
出版信息
Bioorg Khim. 1995 Jul;21(7):506-16.
PMID:7488265
Abstract
Automatic solid phase peptide synthesis using the SynChrom system is described. Problems of swellographic monitoring are discussed. Combined monitoring (swellographic, spectrophotometric, and manometric) of all steps of the synthetic cycle are suggested. Potential applications of the system to liquid column chromatography were demonstrated.
摘要
描述了使用SynChrom系统的自动固相肽合成。讨论了膨胀监测的问题。建议对合成循环的所有步骤进行联合监测（膨胀监测、分光光度监测和压力监测）。展示了该系统在液相柱色谱中的潜在应用。
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