Angiographic trials of lipid-lowering therapy: end of an era?
作者信息
Thompson G R
机构信息
MRC Clinical Sciences Centre, Royal Postgraduate Medical School, Hammersmith Hospital, London.
出版信息
Br Heart J. 1995 Oct;74(4):343-7. doi: 10.1136/hrt.74.4.343.
Abstract
摘要
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Angiographic trials of lipid-lowering therapy: end of an era?降脂治疗的血管造影试验：一个时代的终结？
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Atherosclerosis regression, plaque disruption, and cardiovascular events: a rationale for lipid lowering in coronary artery disease.
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Benefits of lipid-lowering therapy in men with elevated apolipoprotein B are not confined to those with very high low density lipoprotein cholesterol.对于载脂蛋白B升高的男性，降脂治疗的益处并不局限于那些低密度脂蛋白胆固醇水平非常高的男性。
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Triglyceride- and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin.在一项关于洛伐他汀的对照试验中，通过定量冠状动脉造影评估发现，富含甘油三酯和胆固醇的脂蛋白对轻度/中度和重度病变进展有不同影响。
Circulation. 1994 Jul;90(1):42-9. doi: 10.1161/01.cir.90.1.42.
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Effect on coronary atherosclerosis of decrease in plasma cholesterol concentrations in normocholesterolaemic patients. Harvard Atherosclerosis Reversibility Project (HARP) Group.血浆胆固醇浓度降低对血脂正常患者冠状动脉粥样硬化的影响。哈佛动脉粥样硬化逆转项目（HARP）研究小组。
Lancet. 1994 Oct 29;344(8931):1182-6. doi: 10.1016/s0140-6736(94)90506-1.
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Familial Hypercholesterolaemia Regression Study: a randomised trial of low-density-lipoprotein apheresis.
Lancet. 1995 Apr 1;345(8953):811-6. doi: 10.1016/s0140-6736(95)92961-4.
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Combined bezafibrate and simvastatin treatment for mixed hyperlipidaemia.苯扎贝特与辛伐他汀联合治疗混合性高脂血症。
QJM. 1995 Jun;88(6):421-7.
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