Joyce C J, Baker A B, Chartres S
Department of Anaesthesia and Intensive Care, University of Otago, Dunedin, New Zealand.
Br J Anaesth. 1995 Oct;75(4):422-7. doi: 10.1093/bja/75.4.422.
Pulmonary collapse is a common problem after coronary artery bypass graft surgery (CABG). If absorption atelectasis during anaesthesia is an important mechanism in the genesis of pulmonary collapse after CABG, the addition of nitrogen to the inspired gas during anaesthesia should reduce the amount of postoperative collapse. We studied 30 patients who were allocated randomly and prospectively to receive either 100% oxygen or an oxygen-air mixture as the inspired gas during anaesthesia for CABG. Lung volumes, PaO2, and an x-ray atelectasis score were measured before and after surgery to assess the degree of atelectasis. There were no significant differences between the two treatment groups in any of these measurements.
肺萎陷是冠状动脉旁路移植术（CABG）后常见的问题。如果麻醉期间的吸收性肺不张是CABG后肺萎陷发生的重要机制，那么在麻醉期间向吸入气体中添加氮气应能减少术后肺萎陷的程度。我们研究了30例患者，这些患者被随机且前瞻性地分配，在CABG麻醉期间分别接受100%氧气或氧气 - 空气混合物作为吸入气体。在手术前后测量肺容积、动脉血氧分压（PaO2）和X线肺不张评分，以评估肺不张的程度。在这些测量中，两个治疗组之间没有显著差异。
