Joyce C J, Baker A B
Dunedin Public Hospital, New Zealand.
Anaesth Intensive Care. 1995 Dec;23(6):691-6. doi: 10.1177/0310057X9502300606.
During anaesthesia the combination of breathing at low lung volume, the administration of nitrous oxide and high inspired oxygen concentrations produces conditions that favour absorption atelectasis. Measures such as adding nitrogen to the inspired mixture and avoiding high inspired oxygen concentrations would reduce the amount of perioperative atelectasis if gas absorption was important in the genesis of perioperative pulmonary collapse. Experimental results demonstrate that these measures do not protect against atelectasis. This indicates that absorption atelectasis does not play a significant role in the genesis of perioperative pulmonary collapse. Compression atelectasis may be the underlying mechanism.
在麻醉期间，低肺容量呼吸、一氧化二氮的使用和高吸入氧浓度的组合会产生有利于吸收性肺不张的条件。如果气体吸收在围手术期肺萎陷的发生中起重要作用，那么诸如向吸入混合气中添加氮气以及避免高吸入氧浓度等措施将减少围手术期肺不张的发生量。实验结果表明，这些措施并不能预防肺不张。这表明吸收性肺不张在围手术期肺萎陷的发生中不起重要作用。压迫性肺不张可能是潜在机制。
