Blum N A, Freides D
Psychology Department, Emory University, Atlanta, GA 30322, USA.
Schizophr Res. 1995 Aug 15;16(3):217-24. doi: 10.1016/0920-9964(94)00078-m.
Prior work has found evidence of hyperpriming in schizophrenics, which has been related to a persistence of associational activation in thought disorder. We extended this work by administering a lateralized version of the lexical decision task to 10 thought-disordered schizophrenics (TD), 10 non-thought-disordered schizophrenics (NTD), and 11 control subjects to localize the patterns of priming. All subjects were right-handed males. Associated, unassociated, and neutral prime-target pairs were displayed across seven stimulus location combinations: prime and target both presented to the center, left visual field (LVF), or right visual field (RVF); prime presented to the center with target presented to the LVF or RVF; and prime and target presented contralaterally. TD schizophrenics exhibited priming effects comparable to those of the other subject groups, suggesting intact semantic memory structures and memory processes that may be unimpaired under the conditions studied. It is believed that the associative process mediating priming effects found in schizophrenia are later in the sequence than those examined in this study.
先前的研究发现精神分裂症患者存在超启动效应，这与思维障碍中联想激活的持续存在有关。我们通过对10名思维紊乱的精神分裂症患者（TD）、10名非思维紊乱的精神分裂症患者（NTD）和11名对照受试者进行词汇判定任务的偏侧化版本测试，以确定启动模式，从而扩展了这项研究。所有受试者均为右利手男性。相关、不相关和中性的启动刺激-目标刺激对在七种刺激位置组合中呈现：启动刺激和目标刺激均呈现于中央、左视野（LVF）或右视野（RVF）；启动刺激呈现于中央，目标刺激呈现于LVF或RVF；启动刺激和目标刺激呈对侧呈现。TD精神分裂症患者表现出与其他受试者组相当的启动效应，这表明在所研究的条件下，语义记忆结构和记忆过程可能未受损。据信，介导精神分裂症中启动效应的联想过程在序列中比本研究中所考察的过程更靠后。
