Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Int J Psychophysiol. 2010 Feb;75(2):100-6. doi: 10.1016/j.ijpsycho.2009.09.004. Epub 2009 Sep 15.
The use of fMRI and other neuroimaging techniques in the study of cognitive language processes in psychiatric and non-psychiatric conditions has led at times to discrepant findings. Many issues complicate the study of language, especially in psychiatric populations. For example, the use of subtractive designs can produce misleading results. We propose and advocate for a semantic priming parametric approach to the study of semantic processing using fMRI methodology. Implications of this parametric approach are discussed in view of current functional neuroimaging research investigating the semantic processing disturbance of schizophrenia.
在研究精神和非精神疾病条件下的认知语言过程中，使用 fMRI 和其他神经影像学技术有时会导致不一致的发现。许多问题使语言研究变得复杂，尤其是在精神科人群中。例如，使用减法设计可能会产生误导性结果。我们提出并主张使用 fMRI 方法学，采用语义启动参数方法来研究语义处理。鉴于当前正在进行的精神分裂症语义处理障碍的功能性神经影像学研究，讨论了这种参数方法的含义。
