Ludwig J D, Davis C W
Burroughs Wellcome Company, Pharmaceutical Development Laboratories, Greenville, North Carolina, USA.
PDA J Pharm Sci Technol. 1995 Sep-Oct;49(5):253-6.
Instron Residual Seal Force (IRSF) of 13 mm glass vial/rubber closure systems was determined using an Instron 4501 Materials Testing System and computerized data analysis. A series of three cap anvils varying in shape and dimensions were machined to optimize cap anvil performance. Cap anvils with spherical top surfaces and narrow internal dimensions produced uniform stress-deformation curves from which precise IRSF values were derived.
使用Instron 4501材料测试系统和计算机化数据分析来测定13毫米玻璃瓶/橡胶密封系统的英斯特朗残余密封力（IRSF）。加工了一系列三种形状和尺寸各异的瓶盖压砧，以优化瓶盖压砧性能。具有球形顶面和狭窄内部尺寸的瓶盖压砧产生了均匀的应力-变形曲线，由此得出精确的IRSF值。
