Harrison L B, Janjan N
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Hematol Oncol Clin North Am. 1995 Aug;9(4):747-63.
Historically, amputation was the standard local treatment for soft tissue sarcomas of the extremity. Although this procedure provided excellent local control, the adverse impact of this procedure on quality of life was obvious. In an effort to maximize the functional outcome of sarcoma therapy, various groups initiated studies aimed at doing less radical operations in conjunction with radiation therapy.
