Kaye E T, Kaye K M
Harvard Medical School, Boston, Massachusetts, USA.
Infect Dis Clin North Am. 1995 Sep;9(3):547-59.
Topical antibacterial agents offer a useful alternative to systemic agents in certain circumstances. Uses include prophylaxis of infection for burns, traumatic wounds, and intravascular catheters, as well as eradication of S. aureus nasal carriage and treatment of primary and secondary pyodermas. Evidence supporting the use of topical agents for prophylaxis and treatment of skin and superficial wound infections and the indications for use of specific antimicrobials have been reviewed. Although topical agents are widely used, in many instances, data supporting their efficacy are only beginning to emerge.
在某些情况下，局部用抗菌剂为全身用药提供了一种有用的替代方法。其用途包括预防烧伤、创伤性伤口和血管内导管的感染，以及根除金黄色葡萄球菌鼻腔定植和治疗原发性及继发性脓皮病。支持使用局部用抗菌剂预防和治疗皮肤及浅表伤口感染以及特定抗菌药物使用指征的证据已得到综述。尽管局部用抗菌剂被广泛使用，但在许多情况下，支持其疗效的数据才刚刚开始出现。
