通过对尿液中红细胞进行Tamm-Horsfall蛋白免疫细胞化学染色来确定血尿的来源。
Determining the origin of hematuria by immunocytochemical staining of erythrocytes in urine for Tamm-Horsfall protein.
作者信息
Fukuzaki A, Kaneto H, Ikeda S, Orikasa S
机构信息
Department of Urology, Tohoku University School of Medicine, Sendai, Japan.
出版信息
J Urol. 1996 Jan;155(1):248-51.
PURPOSE
We analyzed the feasibility of immunocytochemical staining of urinary erythrocytes for Tamm-Horsfall protein to differentiate renal from nonrenal hematuria.
MATERIALS AND METHODS
Urine samples collected from 74 patients with hematuria were evaluated. Erythrocytes in urine were inspected morphologically and the same samples were immunocytochemically stained with antibody against human Tamm-Horsfall protein.
RESULTS
Erythrocytes in urine were clearly stained for Tamm-Horsfall protein in renal hematuria. Tamm-Horsfall protein immunocytochemistry was more consistent with clinical diagnosis than morphology.
CONCLUSIONS
Immunocytochemical staining of urine erythrocytes for Tamm-Horsfall protein appears to be a reliable tool to differentiate renal from nonrenal hematuria.
目的
我们分析了对尿红细胞进行Tamm-Horsfall蛋白免疫细胞化学染色以区分肾性血尿和非肾性血尿的可行性。
材料与方法
对74例血尿患者收集的尿液样本进行评估。对尿液中的红细胞进行形态学检查，并对相同样本用抗人Tamm-Horsfall蛋白抗体进行免疫细胞化学染色。
结果
在肾性血尿中，尿液红细胞被Tamm-Horsfall蛋白清晰染色。Tamm-Horsfall蛋白免疫细胞化学比形态学更符合临床诊断。
结论
对尿红细胞进行Tamm-Horsfall蛋白免疫细胞化学染色似乎是区分肾性血尿和非肾性血尿的可靠工具。
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