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缺铁和精神刺激对印度尼西亚儿童认知表现及发育的影响。

The effect of iron deficiency and mental stimulation on Indonesian children's cognitive performance and development.

作者信息

Soewondo S

机构信息

Faculty of Psychology, University of Indonesia, Jakarta, Indonesia.

出版信息

Kobe J Med Sci. 1995 Apr;41(1-2):1-17.

PMID:7490909
Abstract

Three studies conducted in Indonesia will be described. Soewondo (12) investigated the relation of iron deficiency and cognitive function and impact of iron supplementation on verbal intelligence, attention and concept learning among iron deficient children without anemia and iron deficient anemic children. Half of 176 children, aged 3-6 years, received elemental Fe for 8 weeks and the other half received placebo. There were significant changes from pre to post intervention evaluations in ferritin, transferrin saturation, free erythrocyte protoporphyrin, and hemoglobin in the iron deficient anemic children. Pre and post treatment psychological test data showed that iron deficiency anemia produced alterations in cognitive processes related to visual attention and concept acquisition. These alterations can be reversed with iron treatment. Idjradinata (4) assessed the impact of iron supplementation on iron deficient infant's mental and psychomotor development. Hundred twenty six subjects aged 12 to 18 month were randomly assigned to either iron treatment or placebo intervention. After 4 months of iron supplementation, the hemoglobin, ferritin and transferrin saturation changed significantly in the iron deficient infants. A developmental delay was observed in the iron deficient anemic infants before intervention and the conditions were reversed after 4 months of iron treatment. Soemiarti (8) examined the effectiveness of a training course given to mothers of children aged 12 to 24 month on the rearing environment and consequently to the child's development. The subjects were 69 mothers of 20-35 years old. The training lasted for 21 days by giving mothers training using the program "Ibu Maju Anak Bermutu". The rearing environment improved, also the child's mental and psychomotor development.

摘要

将介绍在印度尼西亚进行的三项研究。苏温多(12)调查了缺铁与认知功能的关系,以及补铁对无贫血缺铁儿童和缺铁性贫血儿童言语智力、注意力和概念学习的影响。176名3至6岁的儿童中有一半接受了8周的元素铁治疗,另一半接受了安慰剂治疗。缺铁性贫血儿童在干预前和干预后的评估中,铁蛋白、转铁蛋白饱和度、游离红细胞原卟啉和血红蛋白有显著变化。治疗前后的心理测试数据表明,缺铁性贫血会导致与视觉注意力和概念获取相关的认知过程发生改变。这些改变可以通过铁治疗得到逆转。伊德拉迪纳塔(4)评估了补铁对缺铁婴儿心理和精神运动发育的影响。126名12至18个月大的受试者被随机分配到铁治疗组或安慰剂干预组。补铁4个月后,缺铁婴儿的血红蛋白、铁蛋白和转铁蛋白饱和度有显著变化。干预前观察到缺铁性贫血婴儿存在发育迟缓,铁治疗4个月后情况得到逆转。苏埃马尔蒂(8)研究了为12至24个月大儿童的母亲提供的关于养育环境及对儿童发育影响的培训课程的效果。受试者为69名年龄在20至35岁的母亲。培训持续21天,通过使用“母亲助力孩子优秀成长”项目对母亲进行培训。养育环境得到改善,儿童的心理和精神运动发育也得到改善。

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