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[乙酰唑胺治疗新生儿出血后脑室扩张]

[Acetazolamide treatment of a newborn infant with posthemorrhagic cerebral ventricular dilatation].

作者信息

Rubetti P, Elicio M R, Rossi M, Mercatelli D, Rosati C, Berdondini F, Gambi B

机构信息

U.O. di Pediatria, Ospedale S.M. Annunziata, Antella (FI), Italia.

出版信息

Pediatr Med Chir. 1995 Jul-Aug;17(4):359-63.

PMID:7491334
Abstract

We report a case of a male newborn delivered by vacuum at 40 weeks of gestation, who presented perinatal asphyxia, neonatal seizures and ventricular posthemorrhagic dilatation. The newborn was treated with Acetazolamide for 45 days until the reduction of the ventricular dilatation. This case shows the efficacy and the absence of collateral effects of Acetazolamide. This therapy suggests that it may be used as an alternative or an adjunct to lumbar punctures. The pharmacol treatment in the posthemorrhagic ventricular dilatation has not been well studied and there are a few related cases in the literature.

摘要

我们报告一例孕40周经真空吸引分娩的男婴,其出现围产期窒息、新生儿惊厥和脑室出血后扩张。该新生儿接受乙酰唑胺治疗45天,直至脑室扩张减轻。本病例显示了乙酰唑胺的疗效及无副作用。该治疗表明它可作为腰椎穿刺的替代或辅助方法。出血后脑室扩张的药物治疗尚未得到充分研究,文献中相关病例较少。

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