Thomas P S, Agrawal S, Gore M, Geddes D M
Department of Respiratory Medicine, Royal Brompton Hospital, London.
Thorax. 1995 Oct;50(10):1116-8. doi: 10.1136/thx.50.10.1116.
A patient who developed pneumonitis immediately after the administration of carmustine (BCNU), within exactly the same field as previous irradiation, is presented. The patient responded partially to corticosteroids. This case suggests that irradiation causes subclinical sensitisation of the lung and can therefore have an additive effect in precipitating lung damage when another pulmonary toxin is encountered at a later date.
本文报告了一名患者，在给予卡莫司汀（BCNU）后立即在与先前放疗完全相同的区域发生了肺炎。该患者对皮质类固醇治疗有部分反应。此病例表明，放疗会导致肺部发生亚临床致敏，因此当日后遇到另一种肺毒素时，在引发肺损伤方面可能具有累加效应。
