重组因子 XIII 和因子 XIII 浓缩物全身给药后的种植体固定强度和骨整合。多孔表面种植体的种植体固定强度和骨整合动物实验
[Implant fixation strength and osseointegration following systemic administration of recombinant factor XIII and factor XIII concentrate. Animal experiment with implant fixation strength and osseointegration of porous surface implants].
作者信息
Kienapfel H, Wilke A, Dörner P, Jürgensen R, Prinz H, Hettel A, Swain R, Griss P
机构信息
Zentrum Operative Medizin II, Orthopädische Klinik und Poliklinik, Philipps Universität Marburg.
出版信息
Z Orthop Ihre Grenzgeb. 1995 Sep-Oct;133(5):394-400. doi: 10.1055/s-2008-1039944.
30 cylindrical commercially pure titanium fiber porous coated Ti6A14V implants were inserted press-fit into the proximal humeral portion of 30 sheep humeri to determine the systemic effect of recombinant factor XIII and placenta-derived factor XIII concentrate on bone ingrowth and on strength of fixation. For both the recombinant factor XIII and the factor XIII concentrate group the volume fraction of bone ingrowth and the strength of fixation was higher when compared with the control specimens. However the difference was only significant for the factor XIII concentrate group.
将30个圆柱形的商业纯钛纤维多孔涂层Ti6A14V植入物压配到30只绵羊肱骨的近端肱骨部分，以确定重组因子XIII和胎盘衍生因子XIII浓缩物对骨长入和固定强度的全身影响。与对照样本相比，重组因子XIII组和因子XIII浓缩物组的骨长入体积分数和固定强度均更高。然而，差异仅在因子XIII浓缩物组中显著。
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