Felsenberg D
Universitätsklinikum Benjamin Franklin, Osteoporoseforschungsgruppe, Freie Universität Berlin.
Zentralbl Gynakol. 1995;117(10):516-23.
The osteoporosis is a major public health problem occurring primarily among the postmenopausal women. The relationship to the loss of ovarian function is undoubtful. The consequence of this knowledge is to substitute the hormone deficiency. Hormone replacement therapy (HRT) is effective with oral, subcutaneous, parenteral, and transdermal application. The transdermal hormone replacement therapy for prevention and therapy (early phase) of postmenopausal osteoporosis is effective and sure. The osteoprotective effect was demonstrated in multiple studies. The effectiveness of the HRT can be demonstrated by osteodensitometry and measuring markers of bone resorption.
骨质疏松症是一个主要的公共卫生问题，主要发生在绝经后女性中。其与卵巢功能丧失的关系是毋庸置疑的。基于这一认识的结果是补充激素缺乏。激素替代疗法（HRT）通过口服、皮下、肠胃外和经皮应用都是有效的。经皮激素替代疗法用于绝经后骨质疏松症的预防和治疗（早期）是有效且可靠的。多项研究证实了其骨保护作用。HRT的有效性可通过骨密度测定和测量骨吸收标志物来证明。
