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倍他米松对胎鼠肺中磷脂酰胆碱种类组成的影响。

The effect of betamethasone on phosphatidylcholine species composition in fetal rat lungs.

作者信息

Stettner S, Ledwozyw A

机构信息

1st Clinic of General Surgery, Medical Academy, Lublin, Poland.

出版信息

Acta Vet Hung. 1995;43(2-3):297-302.

PMID:7491869
Abstract

After betamethasone treatment, a significant diminution of the monoenoic phosphatidylcholine 32 carbon species (palmitoyl-palmitoleyl phosphatidylcholine and palmitoleyl-palmitoylphosphatidylcholine) and the phosphatidylcholine 34 carbon species (primarily palmitoyl-oleoyl-phosphatidylcholine) could be demonstrated both in absolute and relative terms, while the palmitic acid portion in the phosphatidylcholine fatty acids was nearly unchanged. This is consistent with a significant reduction of the palmitoleic and oleic acid portions of the total phosphatidylcholine fatty acids in the lungs of rat fetuses.

摘要

倍他米松治疗后,无论是从绝对值还是相对值来看,单烯磷脂酰胆碱32碳物种(棕榈酰-棕榈油酰磷脂酰胆碱和棕榈油酰-棕榈酰磷脂酰胆碱)以及磷脂酰胆碱34碳物种(主要是棕榈酰-油酰-磷脂酰胆碱)均显著减少,而磷脂酰胆碱脂肪酸中的棕榈酸部分几乎没有变化。这与大鼠胎儿肺中总磷脂酰胆碱脂肪酸中棕榈油酸和油酸部分的显著减少是一致的。

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