Cavalli F, Alberto P, Jungi W F, Martz G, Barrelet L, Obrecht J P, Brunner K W
Schweiz Med Wochenschr. 1978 Dec 9;108(49):1964-6.
The preliminary results of a still ongoing phase III study in patients with previously untreated metastatic breast cancer are reported. 210 cases are already evaluable. In this study patients are randomized to hormonotherapy either concurrently with combination chemotherapy or alone, chemotherapy being delayed until the occurrence of tumor progression. In both groups patients are further randomly allocated to 3 chemotherapy programs. So far there appear to be differences between remission rates, but not with regard to survival course.
报告了一项仍在进行的针对既往未接受治疗的转移性乳腺癌患者的III期研究的初步结果。已有210例病例可进行评估。在这项研究中，患者被随机分为同时接受激素治疗与联合化疗或仅接受激素治疗两组，化疗推迟至肿瘤进展时进行。两组患者又进一步随机分配到3种化疗方案。到目前为止，缓解率似乎存在差异，但在生存过程方面没有差异。
