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[与激素治疗后进行化疗相比,同时进行激素和药物治疗在转移性乳腺肿瘤治疗中的应用。一项正在进行的研究的初步结果]

[Simultaneous hormonal and drug therapy, compared to hormonal therapy, followed by chemotherapy, in the treatment of metastasizing breast neoplasms. Preliminary results of an ongoing study].

作者信息

Cavalli F, Alberto P, Jungi W F, Martz G, Barrelet L, Obrecht J P, Brunner K W

出版信息

Schweiz Med Wochenschr. 1978 Dec 9;108(49):1964-6.

PMID:749193
Abstract

The preliminary results of a still ongoing phase III study in patients with previously untreated metastatic breast cancer are reported. 210 cases are already evaluable. In this study patients are randomized to hormonotherapy either concurrently with combination chemotherapy or alone, chemotherapy being delayed until the occurrence of tumor progression. In both groups patients are further randomly allocated to 3 chemotherapy programs. So far there appear to be differences between remission rates, but not with regard to survival course.

摘要

报告了一项仍在进行的针对既往未接受治疗的转移性乳腺癌患者的III期研究的初步结果。已有210例病例可进行评估。在这项研究中,患者被随机分为同时接受激素治疗与联合化疗或仅接受激素治疗两组,化疗推迟至肿瘤进展时进行。两组患者又进一步随机分配到3种化疗方案。到目前为止,缓解率似乎存在差异,但在生存过程方面没有差异。

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