van Dissel J T, Zijlmans J M, Kroes A C, Fibbe W E
Department of Infectious Diseases, University Hospital Leiden, The Netherlands.
Ann Hematol. 1995 Nov;71(5):253-5. doi: 10.1007/BF01744375.
Mixed alveolar interstitial pneumonia is a much-feared complication in bone marrow transplant recipients because it carries a high mortality. Many cases in which an etiological agent is identified are due to fungi or cytomegalovirus; rarely, other infectious agents such as Pneumocystis carinii or (para)influenzavirus are involved. In this report we describe a patient who received intense chemotherapy followed by autologous bone marrow transplantation for relapse of testis seminoma and who developed a severe alveolar interstitial pneumonia caused by respiratory syncytial virus in the early posttransplant period. The patient fully recovered after treatment with ribavirin.
混合性肺泡间质肺炎是骨髓移植受者中一种令人恐惧的并发症，因为其死亡率很高。许多已确定病原体的病例是由真菌或巨细胞病毒引起的；很少有其他感染因子如卡氏肺孢子虫或（副）流感病毒参与其中。在本报告中，我们描述了一名患者，他因睾丸精原细胞瘤复发接受了强化化疗，随后进行了自体骨髓移植，并在移植后早期发生了由呼吸道合胞病毒引起的严重肺泡间质肺炎。该患者在接受利巴韦林治疗后完全康复。
