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肯尼亚某农村地区影响母婴健康的因素。十、肯尼亚马查科斯地区儿童血清中抗甲型流感病毒(H3N2)和乙型流感病毒的血凝抑制抗体

Agents affecting health of mother and child in a rural area of Kenya. X. Haemagglutination inhibiting antibodies against influenza A (H3N2) and influenza B virus in sera from children living in the Machakos District of Kenya.

作者信息

Metselaar D, Masurel N, Muller A S, Van Rens M M

出版信息

Trop Geogr Med. 1978 Dec;30(4):523-30.

PMID:749289
Abstract

In the framework of the Machakos Project bloodcollections from random samples of children under 5 years of age and living in a rural area of Kenya were done with regular intervals, Serum samples of two collections were tested for haemagglutination inhibiting antibodies against influenza A and B viruses. The children had been exposed to the Hong Kong/1/68 (H3N2) virus or its variants during one, two or three episodes of circulation and probably to only one epidosde of B/Hong Kong/8/73 virus. The results can be explained by the assumption that 30-40 percent of non-immune children were infected per epidosde of exposure to influenza A and not more than 12 percent per episode of influenza B circulation.

摘要

在马查科斯项目的框架下,对肯尼亚农村地区5岁以下儿童的随机样本定期进行采血,对两次采血的血清样本检测抗甲型和乙型流感病毒的血凝抑制抗体。这些儿童在甲型流感病毒香港/1/68(H3N2)毒株或其变种的一次、两次或三次传播期间接触过该病毒,可能仅在乙型流感病毒香港/8/73毒株的一次传播期间接触过。结果可以用以下假设来解释:在每次接触甲型流感病毒时,30%-40%的未免疫儿童会被感染,而在每次乙型流感病毒传播期间,被感染的儿童不超过12%。

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