Liu K, Ho Y H
Department of Anesthesiology, Veterans General Hospital-Kaohsiung, Taiwan, R.O.C.
Acta Anaesthesiol Sin. 1995 Sep;33(3):195-8.
Streptococcal toxic shock-like syndrome (TSLS), a severe multisystem disorder with rapid progression and fulminant course, is caused by group A beta-hemolytic streptococcal (GAS) infection. The mortality rate is around 30%. It has been reported in the United States and Europe since the 1980s. The recent recognition of this syndrome is thought to stem from the appearance of more virulent strains of streptococci with a greater tendency to produce potent exotoxins than prior ones. Early diagnosis, treatment with penicillin, radical operative debridement and adjuvant therapy with immunoglobulin and plasma exchange may bear a favourable outcome. A case of TSLS who received surgical management in operating room is presented in this paper.
链球菌中毒性休克样综合征(TSLS)是一种严重的多系统疾病,进展迅速且病程凶险,由A组β溶血性链球菌(GAS)感染引起。死亡率约为30%。自20世纪80年代以来,美国和欧洲均有相关报道。人们认为,近期对该综合征的认识源于出现了比以往更具毒性、更易产生强效外毒素的链球菌菌株。早期诊断、青霉素治疗、彻底的手术清创以及免疫球蛋白和血浆置换辅助治疗可能会带来良好的预后。本文介绍了一例在手术室接受手术治疗的TSLS病例。