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95Zr-95Nb在人体中的滞留与排泄

Retention and excretion of 95Zr-95Nb in humans.

作者信息

Thind K S

机构信息

Health Physics Department, Ontario Hydro Nuclear, Whitby, Ontario, Canada.

出版信息

Health Phys. 1995 Dec;69(6):957-60. doi: 10.1097/00004032-199512000-00011.

DOI:10.1097/00004032-199512000-00011
PMID:7493813
Abstract

This note describes the retention and excretion of 95Zr-95Nb in humans based on a recent CANDU experience and a literature survey of reported cases. Two data bases, QUEST and INIS were used for the survey. Three reported cases were discovered: two for occupational exposures and one for public exposure from nuclear weapons fallout. Human lung retention from these three cases, plus whole body retention and some limited fecal excretion data from a recently occurred exposure at a CANDU station, were reviewed and tested against predictions based on ICRP Publication 30 model. Based on the fits of this model to the reported data it seems that the three occupational exposures exhibit class Y behavior while the public exposure exhibits class W behavior. For only one case is the chemical compound known with certainty: ZrO2. Zirconium oxides are currently classified as class W in ICRP Publications 30 and 54. This work confirms a suggestion that oxides of zirconium be classified as class Y and should be taken into account by the ICRP in its future publications.

摘要

本笔记基于加拿大重水铀反应堆(CANDU)的最新经验以及对已报道案例的文献调查,描述了95Zr - 95Nb在人体中的滞留和排泄情况。调查使用了两个数据库,即QUEST和INIS。发现了三个已报道案例:两个职业暴露案例和一个因核武器沉降物导致的公众暴露案例。对这三个案例中的人体肺部滞留情况,以及最近在一个CANDU电站发生的一次暴露中的全身滞留情况和一些有限的粪便排泄数据进行了审查,并根据国际辐射防护委员会(ICRP)第30号出版物模型的预测进行了测试。基于该模型与已报道数据的拟合情况,似乎三个职业暴露案例表现出Y类行为,而公众暴露案例表现出W类行为。只有一个案例能确定其化合物:ZrO₂。氧化锆目前在ICRP第30号和第54号出版物中被归类为W类。这项工作证实了一个建议,即氧化锆应被归类为Y类,ICRP在其未来出版物中应予以考虑。

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