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适形治疗的先进交互式计划技术:高级射束描述与容积映射技术

Advanced interactive planning techniques for conformal therapy: high level beam descriptions and volumetric mapping techniques.

作者信息

McShan D L, Kessler M L, Fraass B A

机构信息

Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, USA.

出版信息

Int J Radiat Oncol Biol Phys. 1995 Dec 1;33(5):1061-72. doi: 10.1016/0360-3016(95)02086-1.

Abstract

PURPOSE

To aid in design of conformal radiation therapy treatment plans involving many conformally shaped fields, this work investigates the use of two methodologies to enhance the ease of interactive treatment planning: high-level beam constructs and beam's-eye view volumetric mapping.

METHODS AND MATERIALS

High-performance computer graphics running on various workstations using a graphical visualization system (AVS) have been used in this work. Software specific to this application has been written in standard FORTRAN and C languages. A new methodology is introduced by defining radiation therapy "fields" to be composed of multiple beam "segments." Fields can then be defined as higher-level entities such as arcs, cones, and other shapes. A "segmental cone" field, for example, is defined by a symmetry axis and a cone angle, and can be used to rapidly place a series of beam segments that converge at the target volume, while reducing the degree of overlap elsewhere. A new beam's-eye view (BEV) volumetric mapping technique is presented to aid in selecting the placement of conformal radiation fields. With this technique, the relative average dose within an organ of interest is calculated for a sampling of isocentric, conformally shaped beams and displayed either as a "globe," which can be combined with the display of anatomical surfaces, or as a two-dimensionally mapped projection. The dose maps from multiple organs can be generated, stacked, or composited with relative weightings to aid in the placement of fields that minimize overlap with critical structures.

RESULTS

The use of these new methodologies is demonstrated for prostate and lung treatment sites and compared to conventional planning techniques.

DISCUSSION

The use of many beams for conformal treatment delivery is difficult with current interactive planning. The use of high-level beam constructs provides a means to quickly specify, place, and configure multiple beam arrangements. The BEV volumetrics aids in the placing of fields, which minimize involvement with critical normal tissues.

CONCLUSIONS

Early experience with the new methodologies suggest that the new methods help to enhance (or at least speed up) the ability of a treatment planner to create optimal radiation treatment field arrangements.

摘要

目的

为了辅助涉及多个适形野的适形放射治疗计划的设计,本研究探讨了两种方法的应用,以提高交互式治疗计划的便捷性:高级射束构建和射野视角体积映射。

方法与材料

本研究使用了运行在各种工作站上的高性能计算机图形技术,并采用了图形可视化系统(AVS)。针对此应用的软件是用标准FORTRAN和C语言编写的。通过将放射治疗“野”定义为由多个射束“段”组成,引入了一种新方法。然后,野可以被定义为诸如弧、圆锥和其他形状的更高级实体。例如,“分段圆锥”野由对称轴和圆锥角定义,可用于快速放置一系列汇聚于靶区的射束段,同时减少其他部位的重叠程度。提出了一种新的射野视角(BEV)体积映射技术,以辅助选择适形放射野的放置位置。使用该技术,针对等中心、适形形状的射束样本,计算感兴趣器官内的相对平均剂量,并以“球体”形式显示,该“球体”可与解剖表面显示相结合,也可作为二维映射投影显示。可以生成、堆叠或合成来自多个器官的剂量图,并赋予相对权重,以辅助放置与关键结构重叠最小的野。

结果

展示了这些新方法在前列腺和肺部治疗部位的应用,并与传统计划技术进行了比较。

讨论

当前的交互式计划难以使用多个射束进行适形治疗。高级射束构建的使用提供了一种快速指定、放置和配置多个射束排列的方法。BEV体积映射有助于放置野,从而使关键正常组织的受照最少。

结论

新方法的早期经验表明,这些新方法有助于提高(或至少加快)治疗计划者创建最佳放射治疗野排列的能力。

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