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地方性胸膜斑与环境因素(作者译)

[Endemic pleural plaques and environmental factors (author's transl)].

作者信息

Neuberger M, Gründorfer W, Haider M, Königshofer R, Müller H W, Raber A, Riedmüller G, Schwaighofer B

出版信息

Zentralbl Bakteriol B. 1978 Dec;167(5-6):391-404.

PMID:749422
Abstract

In an agricultural town in Burgenland (Austria) we found an increased prevalence of pleural plaques. These calcifying thickenings of the pleura are related to minimal asbestos exposure such as is mesothelioma, but they cannot be regarded as a precancerosis. The increased occurrence of pleural plaques in this town of nearly 3500 inhabitants (in which during 1916 to 1945 asbestos was mined) we first found at the chest x-ray archives of a pulmologic hospital, then by mass radiography and blind comparison with control groups. A photofluoroscopy of 300 persons yielded 16 cases with definite pleural plaques (5.3%) among which were 4 cases with suspected asbestosis and another 14 cases with uncertain pleural plaques (4.7%). The 600 control persons showed no such radiological changes. Interviews wich persons detected for pleural plaques at mass radiography gave no indication that they had occupational asbestos exposure. But asbestos was detected in the soil of vineyards and in the dust of the houses. Asbestos was also detectable in the atmospheric dust by x-ray diffraction and scanning electron microscopic techniques.

摘要

在布尔根兰州(奥地利)的一个农业小镇,我们发现胸膜斑的患病率有所上升。这些胸膜的钙化增厚与诸如间皮瘤之类的微量石棉接触有关,但它们不能被视为癌前病变。在这个近3500名居民的小镇(1916年至1945年期间开采石棉)中,胸膜斑发生率的增加首先是在一家肺病医院的胸部X光档案中发现的,然后通过大规模X线摄影以及与对照组的盲法比较得以确认。对300人进行的荧光透视检查发现16例有明确的胸膜斑(5.3%),其中4例疑似石棉肺,另有14例胸膜斑情况不明(4.7%)。600名对照人员未出现此类放射学改变。对在大规模X线摄影中检测出胸膜斑的人员进行访谈,未发现他们有职业性石棉接触的迹象。但在葡萄园土壤和房屋灰尘中检测到了石棉。通过X射线衍射和扫描电子显微镜技术在大气灰尘中也检测到了石棉。

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