Borchardt U, Friedrich P, Nisch G
Zentralbl Neurochir. 1978;39(3):231-40.
In spite of refined diagnostic and therapeutic possibilities, the cerebral abscess continues to be a disease involving great risks. A comparison of surgically treated groups of patients of the periods 1954 to 1962 and 1963 to 1977 does not show any reduction in lethality. This amounted to 15 per cent for the first group and 17.6 per cent for the second group. Extirpation of cerebral abscesses shows the most favourable results of treatment as compared to other surgical procedures. In our opinion, however, it will not remain the only method of treatment in future because it can only be employed if the patient is in a condition permitting an operation. That is why the open abscess treatment will continue to be justified for all cases where cerebral abscesses occur in combination with subdural or epidural empyemas. Certainly, modern anaesthesia methods as well as intensive pre- and postoperative therapy will further reduce the number of patients who are subjected to a primary puncture treatment. Since 1972, we have treated our patients exclusively by abscess exstirpations. Until 1977, none of the total number of 12 patients treated by us has died. We consider the use of scintigraphic and EEG controls of inflammatory cerebral processes to be of decisive importance. These controls enable a differentiation between diffuse and local inflammatory processes which are accompanied by a liquefaction and in this way permit the selection of the optimum time of operation. A basic condition, however, will always be a good interdisciplinary co-operation with infection departments, paediatric and ENT hospitals where in most cases patients suffering from brain abscesses are first admitted.
尽管有了精细的诊断和治疗手段,但脑脓肿仍然是一种风险极大的疾病。对1954年至1962年以及1963年至1977年接受手术治疗的患者组进行比较,未发现致死率有所降低。第一组的致死率为15%,第二组为17.6%。与其他外科手术相比,脑脓肿切除术显示出最有利的治疗效果。然而,我们认为,它未来不会一直是唯一的治疗方法,因为只有在患者状况允许手术时才能采用。这就是为什么对于所有脑脓肿合并硬膜下或硬膜外积脓的病例,开放脓肿治疗仍然是合理的。当然,现代麻醉方法以及强化的术前和术后治疗将进一步减少接受初次穿刺治疗的患者数量。自1972年以来,我们仅通过脓肿切除术治疗患者。到1977年,我们治疗的12名患者中无一死亡。我们认为对脑部炎症过程进行闪烁扫描和脑电图控制具有决定性意义。这些控制能够区分伴有液化的弥漫性和局部炎症过程,从而允许选择最佳手术时间。然而,一个基本条件始终是与感染科、儿科和耳鼻喉医院进行良好的跨学科合作,在大多数情况下,患有脑脓肿的患者首先会被收治到这些医院。