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组胺受体的分子药理学方面

Molecular pharmacological aspects of histamine receptors.

作者信息

Leurs R, Smit M J, Timmerman H

机构信息

Leiden/Amsterdam Center for Drug Research, Department of Pharmacochemistry, Vrije, Universiteit, The Netherlands.

出版信息

Pharmacol Ther. 1995 Jun;66(3):413-63. doi: 10.1016/0163-7258(95)00006-3.

DOI:10.1016/0163-7258(95)00006-3
PMID:7494855
Abstract

In this article, we review the recent developments in the field of histamine research. Besides the description of pharmacological tools for the H1, H2 and H3 receptor, specific attention is paid to both the molecular aspects of the receptor proteins, including the recent cloning of the receptor genes, and their respective signal transduction mechanisms.

摘要

在本文中,我们回顾了组胺研究领域的最新进展。除了描述H1、H2和H3受体的药理学工具外,还特别关注了受体蛋白的分子层面,包括受体基因的最新克隆,以及它们各自的信号转导机制。

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