Bai J C, Gándara M A, Boerr L, Meyer M A, Viola E R, Kremenchutzky S, Crossetti E, Yaquino E
Acta Gastroenterol Latinoam. 1978;8(4):223-8.
Intestinal protein loss was determined in a group of patients with gastric resection by measuring the faecal radioactivity in the stools of 4 days, after intravenous administration of Cl3Cr51. The patients studied were divided in three groups: a) 10 healthy control subjects, b) 5 patients with gastrectomy BII without steatorrhoea, c) 15 patients with gastrectomy BII with steatorrhoea. In group (a) faecal radioactivity was 0.36 +/- 0.26% of the administrated dosis; in group (b) the value was 1.24 +/- 1.07% and in group (c) the activity was 1.40 +/- 1%. Statistically significative difference between groups (a) and (b) ((p less than 0.05) was found between groups (a) and (c) the difference was highly significative (p less than 0.001). However there was no significative difference between groups (b) and (c) (p less than 0.8). We think that serum protein intestinal loss may be, one of the causes of the hipoalbuminemia present in some patients who underwent partial gastrectomy because of gastroduodenal ulcer. Otherwise we did not find a relation between protein loss and steatorrhoea.
通过静脉注射51Cr3Cl后测量4天粪便中的粪便放射性,来测定一组胃切除患者的肠道蛋白质损失。所研究的患者分为三组:a)10名健康对照受试者,b)5名无脂肪泻的毕II式胃切除患者,c)15名有脂肪泻的毕II式胃切除患者。在组(a)中,粪便放射性为给药剂量的0.36±0.26%;在组(b)中,该值为1.24±1.07%,在组(c)中,活性为1.40±1%。在组(a)和组(b)之间发现有统计学意义的差异((p<0.05),在组(a)和组(c)之间差异高度显著(p<0.001)。然而,组(b)和组(c)之间没有显著差异(p<0.8)。我们认为,肠道蛋白质损失可能是一些因胃十二指肠溃疡接受部分胃切除的患者出现低白蛋白血症的原因之一。否则,我们没有发现蛋白质损失与脂肪泻之间的关系。