Ianovskiĭ G V, Stroganova N P, Riabenko D V
Ter Arkh. 1995;67(9):61-3.
Cardiodynamics and contractile myocardial reserves were measured at radionuclide ventriculography and volume loading of the heart (upward position of the legs at 45 degrees) in 43 patients with dilated cardiomyopathy (DCM). The patients displayed a sharp fall in total and regional ejection fractions (BP), stroke volume (SV), cardiac index, a decrease in Vcf and maximum ejection rate (Vmax) in combination with notable cardiomegaly. There were two types of responses to loading test: positive (increased BP, SV, Vcf, Vmax, reduced end-systolic volume) and negative (decreased EP, SV, Vcf, Vmax, increased end-systolic volume) Inotropic effects evidencing the existence or depletion of myocardial contractile reserve. Loading test in DCM patients allows more objective evaluation of the patient's condition and validated therapeutic measures.
对43例扩张型心肌病（DCM）患者进行放射性核素心室造影及心脏容量负荷试验（双腿抬高至45度），测定其心脏动力学和心肌收缩储备。患者表现为总射血分数和局部射血分数（BP）、每搏输出量（SV）、心脏指数急剧下降，Vcf和最大射血速率（Vmax）降低，同时伴有明显的心脏扩大。对负荷试验有两种反应类型：阳性（BP、SV、Vcf、Vmax增加，收缩末期容积减少）和阴性（EP、SV、Vcf、Vmax降低，收缩末期容积增加），这些变力效应证明了心肌收缩储备的存在或耗竭。DCM患者的负荷试验能够更客观地评估患者病情并验证治疗措施。
