Böhler K, Baldt M, Schuller-Petrovic S, Grünwald C, Sellner W, Watzke H, Wolff K
Department of Dermatology, University of Vienna Medical School, Austria.
Thromb Haemost. 1995 Apr;73(4):597-600.
Insufficiency of epifascial veins promotes venous ulceration and increases thromboembolic risk in general surgery patients. Epifascial varicose vein stripping is therefore considered the most effective prophylactic procedure. Thromboembolic risk of patients undergoing this surgical procedure has not yet been prospectively evaluated but appears to be lower than in general surgery patients. The gold standard of preoperative assessment of varicose surgery patients is ascending pressure phlebography, but this technique is invasive, time consuming and costly. We prospectively investigated 100 consecutive varicose vein surgery patients for postoperative thrombosis. Ascending pressure phlebography (APP) and colour coded duplex sonography (CCDS) were performed before and 10 to 21 days after the stripping operation in 100 and 70 patients, respectively. APP revealed no postoperative deep vein thrombosis in all 100 limbs investigated (0 percent; 95 percent confidence interval: 0 to 2.95). With regard to epifascial vein reflux there was good agreement between APP and CCDS (quadratic weighted kappa: 0.76). In 67 out of 73 superficial veins investigated excellent agreement of diagnostic accuracy was found for both diagnostic procedures (91.78 percent; 95 percent confidence interval: 82.96 to 96.92). We conclude that thrombotic risk of varicose vein surgery is low in properly selected patients. CCDS provides a high degree of accuracy in diagnosis of reflux and regular vein morphology and should therefore replace APP; however, APP does remain essential in the preoperative workup of atypical anatomical variants.
筋膜上静脉功能不全可促使普外科患者发生静脉溃疡并增加血栓栓塞风险。因此,筋膜上静脉曲张剥脱术被认为是最有效的预防措施。接受该手术患者的血栓栓塞风险尚未得到前瞻性评估,但似乎低于普外科患者。静脉曲张手术患者术前评估的金标准是上行性静脉造影,但该技术具有侵入性、耗时且费用高昂。我们对连续100例静脉曲张手术患者进行了术后血栓形成的前瞻性研究。分别对100例和70例患者在剥脱手术前及术后10至21天进行了上行性静脉造影(APP)和彩色编码双功超声检查(CCDS)。APP显示在所有100条受检肢体中均未发现术后深静脉血栓形成(0%;95%置信区间:0至2.95)。关于筋膜上静脉反流,APP和CCDS之间具有良好的一致性(二次加权kappa值:0.76)。在73条受检浅静脉中的67条中,两种诊断方法的诊断准确性具有高度一致性(91.78%;95%置信区间:82.96至96.92)。我们得出结论,在选择合适的患者中,静脉曲张手术的血栓形成风险较低。CCDS在反流诊断和正常静脉形态诊断方面具有高度准确性,因此应取代APP;然而,APP在术前评估非典型解剖变异方面仍然至关重要。