Momo F, Wisniewska A, Stevanato R
Department of Physical Chemistry, University of Venice, Italy.
Biochim Biophys Acta. 1995 Nov 22;1240(1):89-94. doi: 10.1016/0005-2736(95)00168-4.
The interaction of spermine with egg-yolk phosphatidylcholine liposomes was investigated. The EPR spin labeling technique evidenced that spermine induces modifications of some membrane functions of biological interest like water permeability and is a possible modulator of diffusion processes for charged and polar molecules. The association constant for a hypothesized complex between spermine and the phosphate group of phosphatidylcholine was evaluated by enzymatic methods.
研究了精胺与蛋黄磷脂酰胆碱脂质体的相互作用。电子顺磁共振自旋标记技术表明，精胺可诱导一些具有生物学意义的膜功能发生改变，如水通透性，并且它可能是带电和极性分子扩散过程的调节剂。通过酶法评估了精胺与磷脂酰胆碱磷酸基团之间假定复合物的缔合常数。
