McKenzie K, van Os J, Fahy T, Jones P, Harvey I, Toone B, Murray R
Department of Psychological Medicine, Kings College Hospital, London.
BMJ. 1995 Nov 18;311(7016):1325-8. doi: 10.1136/bmj.311.7016.1325.
To compare the course and outcome of psychotic illness in a group of Afro-Caribbean patients resident in the United Kingdom and a group of white British patients.
Cohort study of consecutive admissions followed up for four years.
113 patients with psychotic illness of recent onset admitted to two south London hospitals.
Course of illness, history of self harm, social disability, treatment received, and hospital use adjusted for socioeconomic origin.
The Afro-Caribbean group spent more time in a recovered state during the follow up period (adjusted odds ratio 5.0; 95% confidence interval 1.7 to 14.5), were less likely to have had a continuous illness (0.3; 0.1 to 0.8), were less at risk of self harm (0.2; 0.1 to 0.8), and were less likely to have been prescribed antidepressant treatment (0.3; 0.1 to 0.9). There were no differences in hospital use, but the Afro-Caribbean group had more involuntary admissions (8.9; 2.1 to 35.6) and more imprisonments over the follow up period (9.2; 1.6 to 52.3).
Afro-Caribbean patients in the United Kingdom have a better outcome after psychiatric illness than do white people. The combination of high incidence and more benign course of illness of psychotic illness in this group may be due, at least in part, to a greater exposure to precipitants in the social environment.
比较居住在英国的非裔加勒比患者组和英国白人患者组精神病性疾病的病程及结局。
对连续入院患者进行为期四年随访的队列研究。
113例近期发病的精神病性疾病患者,这些患者入住伦敦南部的两家医院。
病程、自伤史、社会残疾状况、接受的治疗以及根据社会经济背景调整后的住院情况。
在随访期间,非裔加勒比患者组处于康复状态的时间更长(调整后的优势比为5.0;95%置信区间为1.7至14.5),持续患病的可能性更小(0.3;0.1至0.8),自伤风险更低(0.2;0.1至0.8),接受抗抑郁治疗的可能性也更小(0.3;0.1至0.9)。两组在住院情况方面没有差异,但非裔加勒比患者组在随访期间有更多非自愿入院情况(8.9;2.1至35.6)和更多入狱情况(9.2;1.6至52.3)。
在英国,非裔加勒比患者患精神疾病后的结局比白人更好。该组精神疾病的高发病率与更良性病程相结合,可能至少部分归因于在社会环境中更多地接触诱发因素。