Rezai K A, Kirchhof B, Heimann K
Universitätsaugenklinik Köln, Germany.
Ger J Ophthalmol. 1995 Sep;4(5):275-8.
We evaluated the posterior drainage of saline in cadaver bovine eyes using different experimental procedures. The saline perfusion via a pars plana infusion into the vitreous cavity was measured in the following 5 different groups of 20 enucleated bovine eyes: 1, control; 2, vitrectomy; 3, vitrectomy + retinectomy; 4, vitrectomy + retinectomy + removal of retinal pigment epithelium (RPE); and 5, vitrectomy + retinectomy + removal of RPE + choroidectomy. The mean values obtained for the facility of saline outflow were as follows group 1, 0.0458 microliter min-1 mmHg-1; group 2, 0.0393 microliter min-1; group 3, 0.1308 microliter min-1 mmHg-1; group 4, 0.2288 microliter min-1; and group 5, 0.9985 microliter/min-1 mmHg-1. The retina appeared to be the major barrier to fluid movement from the vitreous to the chorioid, perhaps due to the lack of extracellular space and to the tight and impervious structure of the retina. The barrier function of the retina may explain the hypotony seen after rhegmatogenous retinal detachment and the decrease in intraocular pressure observed after the removal of silicone oil in eyes that had undergone retinectomy. Our results suggest that the reduction in intraocular pressure occurring after retinectomy is attributable to the new drainage pathway.
我们使用不同的实验方法评估了牛尸体眼球中盐水的后部引流情况。通过平坦部向玻璃体腔注入盐水进行灌注，在以下5组每组20只摘除的牛眼球中测量了盐水灌注量：1组，对照组；2组，玻璃体切除术组；3组，玻璃体切除术+视网膜切除术组；4组，玻璃体切除术+视网膜切除术+视网膜色素上皮（RPE）去除组；5组，玻璃体切除术+视网膜切除术+RPE去除+脉络膜切除术组。盐水流出率的平均值如下：1组，0.0458微升·分钟⁻¹·毫米汞柱⁻¹；2组，0.0393微升·分钟⁻¹；3组，0.1308微升·分钟⁻¹·毫米汞柱⁻¹；4组，0.2288微升·分钟⁻¹；5组，0.9985微升·分钟⁻¹·毫米汞柱⁻¹。视网膜似乎是液体从玻璃体流向脉络膜的主要屏障，这可能是由于细胞外间隙的缺乏以及视网膜紧密且不透水的结构所致。视网膜的屏障功能可能解释了孔源性视网膜脱离后出现的低眼压以及视网膜切除术后硅油取出后观察到的眼压降低。我们的结果表明，视网膜切除术后眼压的降低归因于新的引流途径。
